Anastrozole: a medicine to treat and prevent breast cancer
Five patients (18%) experienced adverse reactions thatwere considered possibly related to ARIMIDEX. These were nausea, acne, pain inan extremity, increased alanine transaminase and aspartate transaminase, andallergic dermatitis. A randomized, double-blind, placebo-controlled,multi-center study enrolled 80 boys with pubertal gynecomastia aged 11 to 18years.
What if I miss a dose?
Consult your healthcare professional for medical advice and drug information before taking this medication and report any adverse effects to the FDA. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. ARIMIDEX may cause fetal harm when administered to apregnant woman and offers no clinical benefit to premenopausal women withbreast cancer.
What side effects may I notice from receiving this medication?
- This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition.
- This is not a list of all drugs or health problems that interact with anastrozole.
- Patients should be advised thatARIMIDEX may cause fetal harm.
- There are other drugs available to treat your condition.
A dose-related increasewas observed in the incidence of ovarian and uterine hyperplasia in females. A dose-related increase in theincidence of ovarian hyperplasia was also observed in female mice. Theseovarian changes are considered to be rodent-specific effects of aromatase inhibition and are of questionable significance to humans. The incidence oflymphosarcoma was increased in males and females at the high dose.
Steady-state plasma levels are approximately 3-to 4-foldhigher than levels observed after a single dose of ARIMIDEX. Plasma concentrationsapproach steady-state levels at about 7 days of once daily dosing. https://collaltimmobiliare.it/study-shows-effective-use-of-steroids-for/ Anastrozoleis 40% bound to plasma proteins in the therapeutic range. Patients should be informed thatif they experience tickling, tingling, or numbness they should notify theirhealth care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Before taking anastrozole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
A total of 1021 patients between the ages of 30 and 92years old were randomized to receive trial treatment. Patients were randomizedto receive 1 mg of ARIMIDEX once daily or 20 mg of tamoxifen once daily. Theprimary endpoints for both trials were time to tumor progression, objectivetumor response rate, and safety.
RxList does not provide medical advice, diagnosis or treatment. You are encouraged to report negative side effects of prescription drugs to the FDA. Medicines are sometimes prescribed for purposes otherthan those listed in a Patient Information leaflet. Do not take ARIMIDEX for acondition for which it was not prescribed.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 4 Jun 2024), Cerner Multum™ (updated 17 Jun 2024), ASHP (updated 10 Jun 2024) and others.